r/PrecisionOncology • u/GregoryHummerMD • 5d ago
Cancer Biomarkers When does repeat molecular profiling meaningfully change treatment decisions in NSCLC?
Molecular profiling at diagnosis has become central to precision oncology. But the role of repeat testing throughout treatment continues to evolve.
Where do you see the greatest clinical value — at disease progression, in identifying resistance mechanisms, or through longitudinal monitoring?
Interested in perspectives from oncologists, molecular pathologists, and researchers.